PAW Denosyl Tabs for Cats & Dogs (30's)

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Paw Denosyl tablets contain the active ingredient S-adenosylmethionine (SAMe), a precursor to the antioxidant glutathione. Increased levels of glutathione in the liver may help to protect liver cells from oxidative stress and aid in the maintenance and protection of liver function in the presence of certain drugs, toxins and disease processes.


  • May help protect liver cells in the presence of certain drugs, toxins and disease processes
  • May also help to support healthy brain function in senior dogs
  • Very high safety profile
  • Each pack contains 30 enteric coated tablets


The liver is an incredibly complex organ that performs approximately 1500 different essential biochemical functions. Among its many tasks, the liver is involved in the metabolism and digestion of protein, carbohydrates, fats and vitamins, as well as metabolism of drugs and production of important substances involved in blood clotting. It has an incredible capacity for regeneration and repair, but like any organ can develop disease and potentially failure.

Acute and chronic liver diseases, exposure to toxins such as paracetamol and use of certain drugs including corticosteroids can result in oxidative stress to the cells of the liver (hepatocytes). Supplementation with SAMe, a precursor to the powerful antioxidant Glutathione, can help to reduce oxidative stress caused to hepatocytes, which may help to protect and maintain healthy liver function. Many veterinarians recommend the use of SAMe as an adjunctive treatment for conditions including: chronic hepatitis, hepatic lipidosis, cholangiohepatitis and neoplasia.

This product is for use only under the guidance and supervision of a veterinarian. Your PetPA  recommends that you consult your veterinarian regarding the suitability of this treatment for your pet prior to use.

Dosing information:
Tablets should not be broken or crushed. Administer once daily at least 1 hour before feeding. Some pets may be maintained long term on every other day or once every three day dosage. Tablet may be disguised in a small bite of moist food if necessary. Cats may require a small amount of water immediately after dosing, please consult your veterinarian for further information.

  • <16kg - use 90mg or 225mg tablets
  • 16-29.9kg - 1 tablet
  • 30-54.9kg - 2 tablets
  • >55kg - 3 tablets

Pets with liver disease may benefit from a prescription veterinary diet.

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